Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 1/20 | 0.35 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 6/20 | 0.35 |
| ▸ | RXRB | P28702 | 6/20 | 0.35 |
| ▸ | RXRG | P48443 | 6/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557836 | 0.80 | SLC29A1 (0.43) | ALDH1A1LMNATSHRHTT | |
| SCHEMBL8557834 | 0.78 | SLC29A1 (0.36) | KCNK3KCNK9RXRARXRBRXRG | |
| SCHEMBL8553960 | 0.74 | SLC29A1 (0.59) | RXRARXRBRXRGALDH1A1 | |
| SCHEMBL8553599 | 0.71 | KDR (0.48) | RXRARXRBRXRGNR4A2PTGS1 | |
| SCHEMBL18409631 | 0.70 | KCNH2 (0.49) | RXRARXRBRXRGNR4A2PTGS1 | |
| SCHEMBL8556969 | 0.66 | REV1 (0.53) | ALDH1A1TSHR | |
| SCHEMBL8557576 | 0.66 | MEN1 (0.52) | RXRARXRBHRH1ALDH1A1LMNA | |
| SCHEMBL8552619 | 0.65 | SLC29A1 (0.53) | RXRARXRBRXRGNR4A2PTGS1 | |
| SCHEMBL8554772 | 0.65 | SLC29A1 (0.53) | RXRARXRBRXRGNR4A2PTGS1 | |
| SCHEMBL18409480 | 0.64 | ALDH1A1 (0.54) | KCNK3KCNK9ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582164-B1 | Adenosine re-uptake inhibiting derivatives of diphenyl oxazoles, thiazoles and imidazoles | BRISTOL MYERS SQUIBB CO (US) | 1998-12-23 | — | — | EP | claimed |