Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 5/20 | 0.71 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.63 |
| ▸ | BRD1 | O95696 | 1/20 | 0.63 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | GHSR | Q92847 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MLNR | O43193 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557904 | 0.86 | PKM (0.73) | PKMTRIM24BRD1BRPF1MAPT | |
| SCHEMBL21950002 | 0.80 | MAPT (0.55) | PKMMAPTPLCG2GHSR | |
| SCHEMBL10154341 | 0.79 | PKM (0.66) | PKMTRIM24BRD1BRPF1MAPT | |
| SCHEMBL8558063 | 0.79 | CYP3A4 (0.57) | PKMTRIM24BRD1BRPF1MAPT | |
| SCHEMBL10239988 | 0.78 | PKM (0.67) | PKMTRIM24BRD1BRPF1LMNA | |
| Hydrochloric Acid SCHEMBL9957679 | 0.77 | PKM (0.66) | PKMTRIM24BRD1BRPF1LMNA | |
| SCHEMBL20035962 | 0.75 | PKM (0.65) | PKMTRIM24BRD1BRPF1MAPT | |
| SCHEMBL7819460 | 0.74 | MAPT (0.56) | PKMMAPTLMNAALDH1A1KMT2A | |
| SCHEMBL639690 | 0.73 | PKM (0.58) | PKMTRIM24BRD1BRPF1MAPT | |
| SCHEMBL4521621 | 0.73 | PKM (0.58) | PKMTRIM24BRD1BRPF1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828733-A1 | BENZOPYRANS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Novartis AG (CH) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996037490-A1 | BENZOPYRANS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NOVARTIS AG (CH) | 1996-11-28 | — | — | WO | disclosed |