Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | MGLL | Q99685 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557978 | 0.87 | CA1 (0.62) | TSHRPKMKMT2AMAPTRAB9A | |
| SCHEMBL6647657 | 0.83 | PKM (0.61) | TSHRPKMKMT2ASLC6A2SLC6A3 | |
| SCHEMBL28683220 | 0.82 | KMT2A (0.50) | KMT2ASLC6A2SLC6A3TDP1MAPT | |
| SCHEMBL22388846 | 0.82 | KMT2A (0.76) | TSHRPKMKMT2ASLC6A2SLC6A3 | |
| SCHEMBL7900071 | 0.82 | TSHR (0.58) | TSHRPKMKMT2ASLC6A2SLC6A3 | |
| SCHEMBL5597240 | 0.80 | TDP1 (0.59) | TSHRKMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL26127977 | 0.80 | TDP1 (0.59) | TSHRKMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL4910233 | 0.79 | TSHR (0.54) | TSHRPKMKMT2ASLC6A2SLC6A3 | |
| SCHEMBL9233919 | 0.79 | TSHR (0.62) | TSHRPKMKMT2ASLC6A2SLC6A3 | |
| SCHEMBL2969506 | 0.79 | ALDH1A1 (0.70) | TSHRPKMKMT2ASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0586379-B1 | POLYMERISATION REGULATION | COMMW SCIENT IND RES ORG (AU) | 1998-05-20 | — | — | EP | disclosed |
| US-5739228-A | Polymerization using thionoester compounds as chain transfer agents | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1998-04-14 | — | — | US | disclosed |
| EP-0586379-A1 | POLYMERISATION REGULATION | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1994-03-16 | — | — | EP | disclosed |
| EP-0586379-A4 | POLYMERISATION REGULATION. | COMMW SCIENT IND RES ORG (AU) | 1993-12-10 | — | — | EP | disclosed |
| WO-1992013903-A1 | POLYMERISATION REGULATION | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1992-08-20 | — | — | WO | disclosed |