Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560966 | 0.96 | AR (0.48) | ARFFAR1FFAR4MAPTPTPN2 | |
| SCHEMBL9025890 | 0.93 | AR (0.45) | ARPTPN1BCL2L1MCL1MEN1 | |
| SCHEMBL8553642 | 0.92 | AR (0.46) | ARNPC1RAB9AMAPTPTPN2 | |
| SCHEMBL9026918 | 0.90 | AR (0.45) | ARFFAR1FFAR4MAPTPTPN2 | |
| SCHEMBL8557266 | 0.89 | AR (0.51) | ARMAPTPTPN2PTPN1PTPN5 | |
| SCHEMBL8556744 | 0.89 | GRM5 (0.44) | ARPTPN2PTPN1PTPN5 | |
| SCHEMBL8556035 | 0.87 | MEN1 (0.45) | ARBCL2L1MCL1GAAHPGD | |
| SCHEMBL8555993 | 0.87 | HPGD (0.46) | MAPTPTPN2PTPN1PTPN5GAA | |
| SCHEMBL8560603 | 0.86 | GRM5 (0.44) | ARMAPTPTPN2PTPN1PTPN5 | |
| SCHEMBL8558776 | 0.86 | MAPT (0.44) | ARRAB9AMAPTPTGDR2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |