Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GRM5 | P41594 | 5/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556035 | 0.95 | MEN1 (0.45) | ARBCL2L1MCL1NR4A2MEN1 | |
| SCHEMBL8557997 | 0.93 | AR (0.51) | ARBCL2L1MCL1PTPN1MEN1 | |
| SCHEMBL8560966 | 0.89 | AR (0.48) | ARBCL2L1MCL1PTPN1MEN1 | |
| SCHEMBL8553642 | 0.86 | AR (0.46) | ARBCL2L1MCL1PTPN1MEN1 | |
| SCHEMBL9026048 | 0.85 | MEN1 (0.50) | ARBCL2L1MCL1PTPN1NR4A2 | |
| SCHEMBL8553921 | 0.85 | MEN1 (0.48) | BCL2L1MCL1NR4A2MEN1KMT2A | |
| SCHEMBL9026918 | 0.84 | AR (0.45) | ARMCL1PTPN1MEN1KMT2A | |
| SCHEMBL8557266 | 0.83 | AR (0.51) | ARBCL2L1MCL1PTPN1MEN1 | |
| SCHEMBL8556744 | 0.82 | GRM5 (0.44) | ARPTPN1GRM5KAT6A | |
| SCHEMBL8558890 | 0.81 | CCR2 (0.41) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699192-A1 | SUBSTITUTED OXAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-03-06 | — | — | EP | claimed |
| WO-1994027980-A1 | SUBSTITUTED OXAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1994-12-08 | — | — | WO | claimed |