Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PLEC | Q15149 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025944 | 0.97 | MAPT (0.52) | TP53MAPTKMT2ATSHRCYP2C9 | |
| SCHEMBL8556510 | 0.88 | KDM4E (0.51) | TP53MAPTKMT2AMEN1KDM4E | |
| SCHEMBL9026868 | 0.87 | MAPT (0.42) | TP53MAPTKMT2ATSHRCYP2C9 | |
| SCHEMBL8555985 | 0.83 | NR4A2 (0.54) | MAPTKMT2ACYP2C9MEN1KDM4E | |
| SCHEMBL8555034 | 0.82 | ALDH1A1 (0.53) | TP53MAPTKMT2ATSHRCYP2C9 | |
| SCHEMBL8556794 | 0.82 | KMT2A (0.52) | TP53MAPTKMT2ATSHRCYP2C9 | |
| SCHEMBL8560085 | 0.81 | KDM4E (0.51) | TP53MAPTKMT2ATSHRCYP2C9 | |
| SCHEMBL8555804 | 0.79 | TP53 (0.46) | TP53MAPTKMT2ATSHRCYP2C9 | |
| SCHEMBL23833719 | 0.78 | ALDH1A1 (0.51) | TP53MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8560630 | 0.77 | MAPT (0.49) | TP53MAPTKMT2ATSHRCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |