Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CCR4 | P51679 | 1/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025944 | 0.92 | MAPT (0.52) | KDM4EKMT2AMAPTTP53HSD17B10 | |
| SCHEMBL8558011 | 0.88 | TP53 (0.55) | KDM4EKMT2AMAPTTP53HSD17B10 | |
| SCHEMBL8555985 | 0.87 | NR4A2 (0.54) | KDM4EKMT2AMAPTHSD17B10ALDH1A1 | |
| SCHEMBL9026868 | 0.84 | MAPT (0.42) | KDM4EKMT2AMAPTTP53HSD17B10 | |
| SCHEMBL8560588 | 0.80 | KDM4E (0.51) | KDM4EKMT2AHSD17B10ALDH1A1HPGD | |
| SCHEMBL8555950 | 0.80 | TSHR (0.44) | KDM4EKMT2AMAPTTP53CCR4 | |
| SCHEMBL8560767 | 0.78 | NR4A2 (0.48) | KDM4EKMT2AALDH1A1HPGDPTGS1 | |
| SCHEMBL9025484 | 0.77 | KDM4E (0.48) | KDM4EKMT2AHSD17B10ALDH1A1HPGD | |
| SCHEMBL8560566 | 0.76 | NR4A2 (0.47) | KDM4EKMT2AALDH1A1HPGDPTGS1 | |
| SCHEMBL8554882 | 0.76 | NR4A2 (0.57) | KDM4EKMT2AMAPTTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |