Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555950 | 0.90 | TSHR (0.44) | ALDH1A1CYP2C9CYP2C19SMN1; SMN2TP53 | |
| SCHEMBL8560085 | 0.89 | KDM4E (0.51) | ALDH1A1CYP2C9CYP2C19SMN1; SMN2TP53 | |
| SCHEMBL8555804 | 0.88 | TP53 (0.46) | ALDH1A1CYP2C9CYP2C19SMN1; SMN2TP53 | |
| SCHEMBL8554882 | 0.85 | NR4A2 (0.57) | ALDH1A1CYP2C9CYP2C19TP53MAPT | |
| SCHEMBL8558805 | 0.83 | ALDH1A1 (0.53) | ALDH1A1CYP2C9CYP2C19SMN1; SMN2TP53 | |
| SCHEMBL8560630 | 0.82 | MAPT (0.49) | ALDH1A1CYP2C9CYP2C19TP53MAPT | |
| SCHEMBL8558011 | 0.82 | TP53 (0.55) | ALDH1A1CYP2C9CYP2C19SMN1; SMN2TP53 | |
| SCHEMBL8560767 | 0.81 | NR4A2 (0.48) | ALDH1A1CYP2C9CYP2C19KMT2AMEN1 | |
| SCHEMBL8554937 | 0.80 | MAPT (0.44) | ALDH1A1CYP2C9CYP2C19TP53MAPT | |
| SCHEMBL8557930 | 0.80 | HSD11B1 (0.44) | ALDH1A1CYP2C9CYP2C19MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |