SCHEMBL8558061

SCHEMBL8558061

COC(OC)(OC)N1C(=O)NC2NC(=O)NC21

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.41
ABL1 P00519 2/20 0.41
RIN1 Q13671 2/20 0.41
MAPT P10636 1/20 0.41
KDM4E B2RXH2 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11879165 0.70 TDP1 (0.41) TDP1ABL1RIN1MAPTKDM4E
SCHEMBL192937 0.67 TDP1 (0.53) TDP1ABL1RIN1MAPTKDM4E
SCHEMBL723098 0.67 TDP1 (0.57) TDP1ABL1RIN1MAPTKDM4E
Methoxymethane SCHEMBL1711287 0.65 ABL1 (0.34) TDP1ABL1RIN1MAPT
SCHEMBL725117 0.64 TDP1 (0.54) TDP1ABL1RIN1MAPTKDM4E
SCHEMBL1714250 0.63 MAPT (0.48) TDP1ABL1RIN1MAPTKDM4E
SCHEMBL5500844 0.63 MAPT (0.48) TDP1ABL1RIN1MAPTKDM4E
SCHEMBL192058 0.63 TDP1 (0.68) TDP1ABL1RIN1MAPTKDM4E
SCHEMBL16859552 0.63 TDP1 (0.44) TDP1ABL1RIN1MAPTKDM4E
SCHEMBL6009927 0.62 TDP1 (0.46) TDP1ABL1RIN1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0520180-B1 Process for the preparation of monomeric tetramethoxymethylglycoluril CYTEC TECH CORP (US) 1998-12-30 EP disclosed
US-5180835-A PROCESS FOR THE PREPARATION OF MONOMERIC TETRAMETHOXYMETHYLGLYCOLORIL AMERICAN CYANAMID COMPANY (US) 1993-01-19 US disclosed
EP-0520180-A2 Process for the preparation of monomeric tetramethoxymethylglycoluril CYTEC TECHNOLOGY CORP. (US) 1992-12-30 EP disclosed