SCHEMBL1714250

SCHEMBL1714250

O=C1NC2NC(=O)N(I)C2N1

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.48
TDP1 Q9NUW8 3/20 0.44
ABL1 P00519 2/20 0.44
RIN1 Q13671 2/20 0.44
KDM4E B2RXH2 2/20 0.36
KMT2A Q03164 1/20 0.36
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5500844 0.71 MAPT (0.48) MAPTTDP1ABL1RIN1KDM4E
SCHEMBL11145933 0.70 TDP1 (0.72) MAPTTDP1ABL1RIN1KDM4E
SCHEMBL4712146 0.67 MAPT (0.44) MAPTTDP1ABL1RIN1KDM4E
SCHEMBL192058 0.67 TDP1 (0.68) MAPTTDP1ABL1RIN1KDM4E
SCHEMBL18106267 0.67 TDP1 (0.58) MAPTTDP1ABL1RIN1KDM4E
SCHEMBL924239 0.67 TDP1 (0.58) MAPTTDP1ABL1RIN1KDM4E
SCHEMBL36250 0.66 MAPT (0.39) MAPTTDP1ABL1RIN1
SCHEMBL16859574 0.64 OPRM1 (0.44) MAPTTDP1ABL1RIN1KDM4E
SCHEMBL18106282 0.64 TDP1 (0.64) MAPTTDP1ABL1RIN1KDM4E
Water SCHEMBL7027290 0.63 MAPT (0.37) MAPTTDP1ABL1RIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140187791-A1 Carbazole Derivative and Method for Producing the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-07-03 US claimed
US-8669373-B2 Carbazole derivative and method for producing the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-03-11 US claimed
EP-2166001-B1 Carbazole Derivative and Method for Producing the Same SEMICONDUCTOR ENERGY LAB (JP) 2011-07-20 EP claimed
US-20100076201-A1 Carbazole Derivative and Method for Producing the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-03-25 US claimed
EP-2166001-A1 Carbazole Derivative and Method for Producing the Same Semiconductor Energy Laboratory Co., Ltd. (JP) 2010-03-24 EP claimed
US-20170125704-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-05-04 US disclosed
US-20140187791-A1 Carbazole Derivative and Method for Producing the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-07-03 US disclosed
US-8669373-B2 Carbazole derivative and method for producing the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-03-11 US disclosed
EP-2330097-B1 Carbazole derivative and method for producing the same SEMICONDUCTOR ENERGY LAB (JP) 2013-01-23 EP disclosed
EP-2166001-B1 Carbazole Derivative and Method for Producing the Same SEMICONDUCTOR ENERGY LAB (JP) 2011-07-20 EP disclosed
US-7960566-B2 Anthracene derivative and light-emitting devices, electronic devices, and lighting device using the anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-06-14 US disclosed
EP-2330097-A1 Carbazole derivative and method for producing the same Semiconductor Energy Laboratory Co, Ltd. (JP) 2011-06-08 EP disclosed
EP-2166001-A1 Carbazole Derivative and Method for Producing the Same Semiconductor Energy Laboratory Co., Ltd. (JP) 2010-03-24 EP disclosed
US-20100069647-A1 Carbazole Derivative, Light-Emitting Element Material, Light-Emitting Element, and Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-03-18 US disclosed
WO-2010005066-A1 CARBAZOLE DERIVATIVE, LIGHT-EMITTING ELEMENT MATERIAL, LIGHT-EMITTING ELEMENT, AND LIGHT-EMITTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-01-14 WO disclosed
EP-2110369-A1 Method of synthesizing 9-aryl-10-iodoanthracene derivative and light-emitting material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-10-21 EP disclosed
EP-2110369-A1 Method of synthesizing 9-aryl-10-iodoanthracene derivative and light-emitting material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-10-21 EP disclosed
US-20090247795-A1 Method of Synthesizing 9-Aryl-10-Iodoanthracene Derivative and Light-Emitting Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-10-01 US disclosed
US-20090247795-A1 Method of Synthesizing 9-Aryl-10-Iodoanthracene Derivative and Light-Emitting Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-10-01 US disclosed
US-20090247795-A1 Method of Synthesizing 9-Aryl-10-Iodoanthracene Derivative and Light-Emitting Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-10-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170125704-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device AHR, ARNT, CRY1 MAPT 1927/4885TDP1 3842/4885ABL1 1299/4885
US-20100069647-A1 Carbazole Derivative, Light-Emitting Element Material, Light-Emitting Element, and Light-Emitting Device CRY1, CHRM1, CYP1A1 MAPT 2426/4885TDP1 2025/4885ABL1 1163/4885
US-20090247795-A1 Method of Synthesizing 9-Aryl-10-Iodoanthracene Derivative and Light-Emitting Material NISCH, TPO, INTS9 MAPT 2573/4885TDP1 3573/4885ABL1 55/4885
US-20100076201-A1 Carbazole Derivative and Method for Producing the Same AADAC, CYP1A1, CYP1B1 MAPT 4455/4885TDP1 2340/4885ABL1 1969/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.