SCHEMBL16859552

SCHEMBL16859552

CC(C)N1C(=O)NC2NC(=O)NC21

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.44
ABL1 P00519 3/20 0.44
RIN1 Q13671 3/20 0.44
MAPT P10636 1/20 0.44
PKM P14618 1/20 0.40
SIRT5 Q9NXA8 1/20 0.40
KDM4E B2RXH2 2/20 0.36
KMT2A Q03164 1/20 0.36
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4712146 0.79 MAPT (0.44) TDP1ABL1RIN1MAPTPKM
SCHEMBL1310366 0.79 TDP1 (0.41) TDP1ABL1RIN1MAPTPKM
SCHEMBL8651114 0.73 TDP1 (0.50) TDP1ABL1RIN1MAPTPKM
SCHEMBL721699 0.67 TDP1 (0.53) TDP1ABL1RIN1MAPTPKM
SCHEMBL5500844 0.67 MAPT (0.48) TDP1ABL1RIN1MAPTKDM4E
SCHEMBL192058 0.67 TDP1 (0.68) TDP1ABL1RIN1MAPTPKM
SCHEMBL11145933 0.65 TDP1 (0.72) TDP1ABL1RIN1MAPTPKM
SCHEMBL7992491 0.65 TDP1 (0.50) TDP1ABL1RIN1MAPTPKM
SCHEMBL196680 0.64 MAPT (0.46) TDP1ABL1RIN1MAPTKDM4E
SCHEMBL11879165 0.63 TDP1 (0.41) TDP1ABL1RIN1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105505146-B Organic bottom antireflective coating composition for nano-photoetching 罗门哈斯电子材料韩国有限公司 2018-11-20 CN disclosed
US-20150185614-A1 ORGANIC BOTTOM ANTIREFLECTIVE COATING COMPOSITION FOR NANOLITHOGRAPHY DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2015-07-02 US disclosed