Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8417011 | 0.88 | CYP4F2 (0.52) | NOTUMKDM4ESMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL8414043 | 0.86 | NOTUM (0.46) | NOTUMKDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL8415367 | 0.83 | SCN9A (0.38) | EGFRSRCKDM4ESMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8576052 | 0.81 | TDP1 (0.48) | SMN1; SMN2ALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL31058340 | 0.79 | MEN1 (0.49) | KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL8572572 | 0.77 | MEN1 (0.38) | KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL7275157 | 0.76 | HRH3 (0.44) | KDM4EHSD17B10MEN1KMT2ALMNA | |
| SCHEMBL10438855 | 0.73 | CYP4F2 (0.58) | EGFRSRCKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL27650487 | 0.73 | MAPT (0.43) | KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL8414036 | 0.71 | HSP90AA1 (0.46) | KDM4ESMN1; SMN2ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827849-A | HAVING INHIBITORY EFFECT ON INFLAMMATION AND BONE DEGRADATION, ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASIS-INHIBITING EFFECT | KARL THOMAE GMBH (DE) | 1998-10-27 | — | — | US | disclosed |
| US-5681841-A | PREVENTION CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1997-10-28 | — | — | US | disclosed |