Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558186 | 0.83 | NOTUM (0.42) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8417011 | 0.81 | CYP4F2 (0.52) | ALDH1A1KDM4EMAPTCYP1A2CYP3A4 | |
| SCHEMBL8414043 | 0.80 | NOTUM (0.46) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL27650487 | 0.79 | MAPT (0.43) | SCN9AALDH1A1KDM4EMAPTCYP1A2 | |
| SCHEMBL31058340 | 0.79 | MEN1 (0.49) | SCN9AALDH1A1KDM4EMAPTCYP1A2 | |
| Hydrochloric Acid SCHEMBL8576052 | 0.77 | TDP1 (0.48) | ALDH1A1POLBCYP3A4MEN1KMT2A | |
| SCHEMBL3957390 | 0.75 | NPC1 (0.53) | SCN9AALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL8415373 | 0.74 | ITGB3 (0.41) | ALDH1A1POLBMEN1KMT2ALMNA | |
| SCHEMBL8572572 | 0.72 | MEN1 (0.38) | SCN9AALDH1A1KDM4EMAPTCYP1A2 | |
| SCHEMBL3957395 | 0.72 | SCN9A (0.47) | SCN9AALDH1A1KDM4EMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880284-A | HAVING ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASES-INHIBITING EFFECTS | DR. KARL THOMAE GMBH (DE) | 1999-03-09 | — | — | US | disclosed |
| US-5681841-A | PREVENTION CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1997-10-28 | — | — | US | disclosed |