Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.36 |
| ▸ | NMT1 | P30419 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8170812 | 0.92 | CHRM1 (0.57) | CHRM1CHRM3PLCG1SLC6A4MAPT | |
| SCHEMBL8171108 | 0.71 | ALDH1A1 (0.57) | CHRM1CHRM3NMT1HTR6 | |
| SCHEMBL2451404 | 0.71 | PLCG1 (0.60) | PLCG1MAPTCA1CA2CA4 | |
| SCHEMBL15916256 | 0.71 | PLCG1 (0.60) | PLCG1MAPTCA1CA2CA4 | |
| SCHEMBL28023659 | 0.71 | PLCG1 (0.60) | PLCG1MAPTCA1CA2CA4 | |
| SCHEMBL15916086 | 0.70 | MAPT (0.49) | PLCG1MAPTCA1CA2CA4 | |
| SCHEMBL15915195 | 0.69 | PLCG1 (0.58) | PLCG1MAPTCA1CA2CA4 | |
| SCHEMBL15915533 | 0.68 | PLCG1 (0.61) | PLCG1CA1CA2CA4CA6 | |
| SCHEMBL15917691 | 0.68 | MAPT (0.74) | PLCG1MAPTCA1CA2CA4 | |
| SCHEMBL7885967 | 0.67 | ITGB3 (0.41) | CHRM1CHRM3SLC6A4ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832076-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-04-01 | — | — | EP | disclosed |