Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 9/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4435109 | 0.88 | KMT2A (0.43) | ANO1L3MBTL1GAAALDH1A1KDM4E | |
| SCHEMBL8559264 | 0.88 | ANO1 (0.43) | ANO1P2RX7L3MBTL1POLBGAA | |
| SCHEMBL8862726 | 0.88 | P2RX7 (0.39) | P2RX7ALDH1A1KDM4EHTT | |
| SCHEMBL6997846 | 0.85 | MEN1 (0.41) | ANO1ALDH1A1 | |
| SCHEMBL8651766 | 0.83 | P2RX7 (0.47) | ANO1P2RX7L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL8552873 | 0.83 | ALDH1A1 (0.38) | ANO1L3MBTL1ALDH1A1KDM4EHTT | |
| SCHEMBL8654003 | 0.81 | P2RX7 (0.43) | ANO1P2RX7L3MBTL1POLBGAA | |
| SCHEMBL4428397 | 0.81 | MEN1 (0.42) | ANO1P2RX7L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL8862719 | 0.81 | P2RX7 (0.37) | P2RX7L3MBTL1GAAALDH1A1KDM4E | |
| SCHEMBL8862619 | 0.79 | SMN1; SMN2 (0.42) | P2RX7GAAALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847211-A | Substituted 1H-3-Aryl-pyrrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |
| EP-0668267-B1 | Substituted 1H-3-aryl-pyrrolidine-2,4-dione derivatives | BAYER AG (DE) | 1998-04-08 | — | — | EP | disclosed |
| US-5622917-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |
| EP-0668267-A1 | Substituted 1H-3-aryl-pyrrolidine-2,4-dione derivatives | BAYER AG (DE) | 1995-08-23 | — | — | EP | disclosed |