Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL609835 | 0.77 | — | — | |
| SCHEMBL129118 | 0.76 | TSHR (0.57) | TSHR | |
| SCHEMBL6572006 | 0.76 | TSHR (0.33) | TSHR | |
| SCHEMBL269069 | 0.73 | TSHR (0.52) | TSHR | |
| SCHEMBL10644432 | 0.72 | — | — | |
| SCHEMBL7648459 | 0.72 | LMNA (0.33) | — | |
| SCHEMBL2883020 | 0.72 | TSHR (0.38) | TSHR | |
| SCHEMBL4586265 | 0.72 | PRSS1 (0.33) | TSHR | |
| SCHEMBL608947 | 0.71 | KMT2A (0.44) | TSHR | |
| SCHEMBL29214022 | 0.71 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883613-A1 | SULFONAMIDE DERIVATIVES AS 5HT7 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1998-12-16 | — | — | EP | disclosed |
| WO-1997029097-A1 | SULFONAMIDE DERIVATIVES AS 5HT7 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1997-08-14 | — | — | WO | disclosed |