SCHEMBL6572006

SCHEMBL6572006

COC(=N)c1c[c]ccc1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
PRSS1 P07477 2/20 0.32
PRSS2 P07478 2/20 0.32
PRSS3 P35030 2/20 0.32
C1S P09871 1/20 0.30
RECQL P46063 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4586265 0.79 PRSS1 (0.33) TSHRPRSS1PRSS2PRSS3C1S
SCHEMBL6571900 0.79 PDCD1 (0.32)
SCHEMBL3228443 0.79 DGAT1 (0.44) TSHRKMT2A
SCHEMBL6571820 0.79 ALDH1A1 (0.30) TSHR
SCHEMBL8558532 0.76 TSHR (0.33) TSHR
SCHEMBL129118 0.76 TSHR (0.57) TSHR
SCHEMBL6568994 0.75 ALDH1A1 (0.38) TSHR
SCHEMBL3390194 0.74 PRSS1 (0.31) PRSS1PRSS2PRSS3
SCHEMBL4047657 0.73 HDAC3 (0.31) PRSS1PRSS2PRSS3C1SRECQL
SCHEMBL27779236 0.73 ALDH1A1 (0.34) PRSS1PRSS2PRSS3C1SRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108699045-B Substituted 2-oxoimidazolyl carboxamides as pest control agents 拜耳作物科学股份公司 2021-02-12 CN claimed
EP-3414237-B1 SUBSTITUTED 2-OXYIMIDAZOLYL-CARBOXAMIDES AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2020-12-23 EP claimed
US-10647699-B2 Substituted 2-oxyimidazolylcarboxamides as pesticides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-05-12 US claimed
US-20190040042-A1 SUBSTITUTED 2-OXYIMIDAZOLYLCARBOXAMIDES AS PESTICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-02-07 US claimed
EP-0463488-B2 O-Benzyl oxime ethers and fungicides containing them BASF AG (DE) 2004-04-21 EP claimed
US-20220192185-A1 STABILIZATION OF SUSPENSION CONCENTRATES BY HIGHLY SULFONATED LIGNOSULFONATE BASF SE (DE) 2022-06-23 US disclosed
US-20220183278-A1 STABILIZATION OF SUSPENSION CONCENTRATES BY HYDROPHOBIC FUMED SILICA BASF SE (DE) 2022-06-16 US disclosed
US-20220159957-A1 STABILIZATION OF SUSPENSION CONCENTRATES BY ETHOXYLATED RICINOLEIN BASF SE (DE) 2022-05-26 US disclosed
EP-3962269-A1 STABILIZATION OF SUSPENSION CONCENTRATES BY ETHOXYLATED RICINOLEIN BASF SE (DE) 2022-03-09 EP disclosed
WO-2020224944-A1 STABILIZATION OF SUSPENSION CONCENTRATES BY HIGHLY SULFONATED LIGNOSULFONATE BASF SE (DE) 2020-11-12 WO disclosed
WO-2020224943-A1 STABILIZATION OF SUSPENSION CONCENTRATES BY HYDROPHOBIC FUMED SILICA BASF SE (DE) 2020-11-12 WO disclosed
WO-2020224942-A1 STABILIZATION OF SUSPENSION CONCENTRATES BY ETHOXYLATED RICINOLEIN BASF SE (DE) 2020-11-12 WO disclosed
US-20190040042-A1 SUBSTITUTED 2-OXYIMIDAZOLYLCARBOXAMIDES AS PESTICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-02-07 US disclosed
CN-108699045-A Substitution 2- oxo-imidazole yl-carboxamides as pest control agent 拜耳作物科学股份公司 2018-10-23 CN disclosed
EP-0463488-B2 O-Benzyl oxime ethers and fungicides containing them BASF AG (DE) 2004-04-21 EP disclosed
EP-1329160-A2 4-ACYLAMINOPYRAZOLE DERIVATIVES Sankyo Company, Limited (JP) 2003-07-23 EP disclosed
US-RE37839-E1 O-benzyloxime ethers and crop protection agents containing these compounds BASF AKTIENGESELLSCHAFT (DE) 2002-09-10 US disclosed
US-6326399-B1 CONTROLLING INSECTS, ARACHNIDS, NEMATODES BASF AKTIENGESELLSCHAFT (DE) 2001-12-04 US disclosed
US-6316459-B1 O-benzyloxime ethers and crop protection agents containing these compounds BASF AG (DE) 2001-11-13 US disclosed
US-6211190-B1 Pyrimidine derivatives, process and intermediate products for their preparation and pesticides or fungicides containing these derivatives BASF AKTIENGESELLSCHAFT (DE) 2001-04-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220159957-A1 STABILIZATION OF SUSPENSION CONCENTRATES BY ETHOXYLATED RICINOLEIN ERO1A, ERLIN2, ERLIN1 TSHR 3813/4885PRSS1 4352/4885PRSS2 2551/4885
US-20220192185-A1 STABILIZATION OF SUSPENSION CONCENTRATES BY HIGHLY SULFONATED LIGNOSULFONATE LSS, STS, U2SURP TSHR 4730/4885PRSS1 827/4885PRSS2 245/4885
US-10647699-B2 Substituted 2-oxyimidazolylcarboxamides as pesticides DDT, PRXL2A, TSNAX TSHR 978/4885PRSS1 3370/4885PRSS2 1199/4885
US-20220183278-A1 STABILIZATION OF SUSPENSION CONCENTRATES BY HYDROPHOBIC FUMED SILICA RCC1, SAMM50, PIGS TSHR 4520/4885PRSS1 3409/4885PRSS2 1952/4885
US-20190040042-A1 SUBSTITUTED 2-OXYIMIDAZOLYLCARBOXAMIDES AS PESTICIDES DDT, PRXL2A, TSNAX TSHR 978/4885PRSS1 3370/4885PRSS2 1199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.