Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.40 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.40 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.40 |
| ▸ | LIMK2 | P53671 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558072 | 0.93 | PTGS2 (0.46) | PTGS2MAPTTAAR1PTGS1MEN1 | |
| SCHEMBL8557761 | 0.88 | MAPT (0.49) | PTGS2MAPTTAAR1PTGS1MEN1 | |
| SCHEMBL8558401 | 0.87 | MAPT (0.45) | PTGS2MAPTPTGS1MEN1KMT2A | |
| SCHEMBL8558727 | 0.87 | MAPT (0.45) | PTGS2MAPTMEN1KMT2APOLB | |
| SCHEMBL8556139 | 0.84 | MAPT (0.47) | MAPTMEN1KMT2APOLBNPSR1 | |
| SCHEMBL8559953 | 0.84 | AR (0.45) | PTGS2MAPTTAAR1PTGS1MEN1 | |
| SCHEMBL9026918 | 0.82 | AR (0.45) | MAPTMEN1KMT2APOLBNPSR1 | |
| SCHEMBL8555819 | 0.81 | MAPT (0.40) | PTGS2MAPTPTGS1MEN1KMT2A | |
| SCHEMBL8560966 | 0.80 | AR (0.48) | MAPTMEN1KMT2APOLBNPSR1 | |
| SCHEMBL8560329 | 0.79 | PTGS2 (0.52) | PTGS2MAPTPTGS1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |