Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.42 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.42 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | EDNRB | P24530 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560795 | 0.92 | EDNRB (0.43) | MAPTMEN1KMT2APTPN2PTPN1 | |
| SCHEMBL8558401 | 0.89 | MAPT (0.45) | MAPTMEN1KMT2APTPN2PTPN1 | |
| SCHEMBL8558072 | 0.89 | PTGS2 (0.46) | MAPTMEN1KMT2APTPN2PTPN1 | |
| SCHEMBL8558539 | 0.87 | PTGS2 (0.47) | MAPTMEN1KMT2APTPN2PTPN1 | |
| SCHEMBL8556139 | 0.86 | MAPT (0.47) | MAPTMEN1KMT2APTPN2PTPN1 | |
| SCHEMBL8557761 | 0.85 | MAPT (0.49) | MAPTMEN1KMT2APTPN2PTPN1 | |
| SCHEMBL9026918 | 0.84 | AR (0.45) | MAPTMEN1KMT2APTPN2PTPN1 | |
| SCHEMBL8560329 | 0.83 | PTGS2 (0.52) | MAPTMEN1KMT2APTPN2PTPN1 | |
| SCHEMBL8555819 | 0.82 | MAPT (0.40) | MAPTMEN1KMT2APTPN2PTPN1 | |
| SCHEMBL8560966 | 0.82 | AR (0.48) | MAPTMEN1KMT2APTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |