Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.42 |
| ▸ | IL1RN | P18510 | 1/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LIMK2 | P53671 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6431253 | 0.84 | KEAP1 (0.57) | KEAP1IL1RNERAP1ALDH1A1KMT2A | |
| Pyrimidine SCHEMBL467971 | 0.74 | PTPRB (0.36) | KEAP1IL1RNERAP1ALDH1A1KMT2A | |
| Diphenylamine SCHEMBL7524565 | 0.73 | HSD17B10 (0.50) | ALDH1A1KMT2AKDM4EMEN1 | |
| Uracil SCHEMBL28070885 | 0.73 | CRBN (0.46) | KEAP1IL1RNERAP1ALDH1A1KMT2A | |
| SCHEMBL27753867 | 0.73 | AURKA (0.46) | KMT2AKDM4EGRM4MEN1 | |
| SCHEMBL28576 | 0.73 | CA1 (0.33) | CA1CA2CA9 | |
| SCHEMBL19741153 | 0.73 | COMT (0.30) | — | |
| Phenylhydrazine SCHEMBL27512048 | 0.71 | TDP1 (0.54) | ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL16045960 | 0.71 | KEAP1 (0.53) | KEAP1IL1RNERAP1ALDH1A1KMT2A | |
| SCHEMBL31219641 | 0.69 | KEAP1 (0.58) | KEAP1ALDH1A1KMT2AMEN1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1984558-A | Novel herbicide resistance gene | DOW AGROSCIENCES LLC (US) | 2007-06-20 | — | — | CN | disclosed |
| EP-0537611-B1 | Process for the preparation of substituted N-(aryl)-1,2,4-triazolopyrimidine-2-sulfonamides | DOW AGROSCIENCES LLC (US) | 1998-08-12 | — | — | EP | disclosed |
| EP-0434624-B1 | Triazolylsulfonamides | CIBA GEIGY AG (CH) | 1995-02-08 | — | — | EP | disclosed |
| US-5217521-A | Preemergence, postemergence herbicides | CIBA-GEIGY CORPORATION (US) | 1993-06-08 | — | — | US | disclosed |
| US-5217521-A | Preemergence, postemergence herbicides | CIBA-GEIGY CORPORATION (US) | 1993-06-08 | — | — | US | disclosed |
| EP-0434624-A1 | Triazolylsulfonamides | CIBA-GEIGY AG (CH) | 1991-06-26 | — | — | EP | disclosed |
| EP-0434624-A1 | Triazolylsulfonamides | CIBA-GEIGY AG (CH) | 1991-06-26 | — | — | EP | disclosed |