Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 7/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | RYR2 | Q92736 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 3/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563265 | 0.88 | NOX1 (0.61) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL10671438 | 0.85 | NOX1 (0.61) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL8563069 | 0.80 | MEN1 (0.43) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL4510651 | 0.77 | GAA (0.52) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL8558177 | 0.77 | NOX1 (0.58) | NOX1GAAMAPTMEN1KMT2A | |
| Phenothiazine SCHEMBL9074312 | 0.76 | NOX1 (1.00) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL29278502 | 0.76 | NOX1 (0.53) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL29936312 | 0.76 | NOX1 (0.53) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL239600 | 0.76 | NOX1 (1.00) | NOX1GAAMAPTMEN1KMT2A | |
| Benzene SCHEMBL29242182 | 0.75 | NOX1 (0.97) | NOX1GAAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |
| EP-0640592-A1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID COMPANY (US) | 1995-03-01 | — | — | EP | disclosed |