Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | ALPG | P10696 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7477152 | 0.75 | KDM4E (0.40) | ALDH1A1KDM4ETSHRSMN1; SMN2RAB9A | |
| SCHEMBL8044732 | 0.73 | KDM4E (0.52) | ALDH1A1KDM4ETSHRSMN1; SMN2RAB9A | |
| SCHEMBL7482369 | 0.71 | HSD17B10 (0.43) | ALDH1A1KDM4ETSHRSMN1; SMN2RAB9A | |
| SCHEMBL7473547 | 0.67 | ALDH1A1 (0.58) | ALDH1A1KDM4ETSHRSMN1; SMN2RAB9A | |
| SCHEMBL7481507 | 0.64 | KDM4E (0.53) | ALDH1A1KDM4ETSHRSMN1; SMN2RAB9A | |
| SCHEMBL8561717 | 0.64 | SMN1; SMN2 (0.35) | ALDH1A1KDM4ETSHRSMN1; SMN2RAB9A | |
| SCHEMBL8044065 | 0.63 | HSD17B10 (0.47) | ALDH1A1KDM4ETSHRSMN1; SMN2RAB9A | |
| SCHEMBL7476136 | 0.63 | KMT2A (0.41) | ALDH1A1KDM4ETSHRSMN1; SMN2RAB9A | |
| SCHEMBL7476293 | 0.63 | HSD17B10 (0.43) | ALDH1A1KDM4ETSHRSMN1; SMN2RAB9A | |
| SCHEMBL7484099 | 0.62 | ADORA3 (0.43) | ALDH1A1KDM4ESMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883622-A1 | PROTON PUMP INHIBITOR | APOTEX INC. (CA) | 1998-12-16 | — | — | EP | claimed |
| EP-0883606-A1 | PROCESS FOR SCAVENGING THIOLS | APOTEX INC. (CA) | 1998-12-16 | — | — | EP | claimed |
| WO-1997031923-A1 | PROTON PUMP INHIBITOR | APOTEX INC. (CA) | 1997-09-04 | — | — | WO | claimed |
| WO-1997031893-A1 | PROCESS FOR SCAVENGING THIOLS | APOTEX INC. (CA) | 1997-09-04 | — | — | WO | claimed |