Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | FDPS | P14324 | 2/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.36 |
| ▸ | GRM6 | O15303 | 3/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8151869 | 0.83 | LIMK1 (0.48) | LIMK1MEN1ALOX5FDPSBCL2 | |
| SCHEMBL7518124 | 0.81 | LIMK1 (0.46) | LIMK1MEN1ALOX5FDPSBCL2 | |
| SCHEMBL7519571 | 0.78 | LIMK1 (0.49) | LIMK1MEN1ALOX5FDPSBCL2 | |
| SCHEMBL7521021 | 0.76 | GRM6 (0.48) | LIMK1MEN1GRM6CYP1A2CYP3A4 | |
| SCHEMBL7545563 | 0.74 | MAPT (0.50) | LIMK1MEN1GRM6LMNACYP1A2 | |
| SCHEMBL423214 | 0.70 | LIMK1 (0.72) | LIMK1MEN1FDPSBCL2BCL2L1 | |
| SCHEMBL4765789 | 0.68 | LIMK1 (0.68) | LIMK1MEN1FDPSADRB2ADRB1 | |
| SCHEMBL7010058 | 0.65 | ALOX5 (0.40) | LIMK1MEN1ALOX5FDPSADRB2 | |
| SCHEMBL10698380 | 0.65 | ALOX5 (0.48) | LIMK1ALOX5GRM6GRM5HPGD | |
| SCHEMBL16996824 | 0.63 | GRM6 (0.52) | LIMK1MEN1ALOX5GRM6GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0862573-A1 | THIENOPYRIDINE DERIVATIVES AS GONADOTROPIN RELEASING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 1998-09-09 | — | — | EP | disclosed |
| US-5744479-A | PITUITARY HORMONE INHIBITOR | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-04-28 | — | — | US | disclosed |
| WO-1997014697-A1 | THIENOPYRIDINE DERIVATIVES AS GONADOTROPIN RELEASING HORMONE ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-04-24 | — | — | WO | disclosed |