Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 4/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | HTR2B | P41595 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555923 | 0.72 | PDE2A (0.44) | POLBALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL4953186 | 0.70 | HTR2C (0.46) | POLBHTR2CHTR2AHTR2BALDH1A1 | |
| SCHEMBL7843954 | 0.69 | ALDH1A1 (0.37) | POLBALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL4958926 | 0.67 | HTR2C (0.46) | HTR2CHTR2AHTR2BALDH1A1MAPK1 | |
| SCHEMBL4958708 | 0.66 | HTR2C (0.47) | HTR2CHTR2AHTR2BALDH1A1MAPK1 | |
| SCHEMBL4956864 | 0.65 | HTR2C (0.46) | HTR2CHTR2AHTR2BALDH1A1L3MBTL1 | |
| SCHEMBL9842102 | 0.64 | ALDH1A1 (0.41) | POLBALDH1A1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL4955856 | 0.64 | HTR2C (0.40) | HTR2CHTR2AHTR2BALDH1A1L3MBTL1 | |
| SCHEMBL18459329 | 0.63 | CA2 (0.61) | POLBALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL7843808 | 0.62 | HTR2C (0.46) | HTR2CHTR2AHTR2BALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591528-B1 | PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVE AND ANTI-INFLAMMATORY CONTAINING THE SAME | OTSUKA PHARMA CO LTD (JP) | 1998-12-23 | — | — | EP | disclosed |
| EP-0591528-A1 | PYRAZOLO 1,5-a]PYRIMIDINE DERIVATIVE AND ANTI-INFLAMMATORY CONTAINING THE SAME | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1994-04-13 | — | — | EP | disclosed |