SCHEMBL8559280

SCHEMBL8559280

CC(C)(C)C(=O)CC(=O)C(F)(F)Cl

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11516509 0.87 ALDH1A1 (0.32) KMT2A
SCHEMBL11974568 0.84 KMT2A (0.32) NPC1RAB9AKMT2A
SCHEMBL93393 0.81 KMT2A (0.39) NPC1RAB9AKMT2A
SCHEMBL4837194 0.81 KMT2A (0.39) NPC1RAB9AKMT2A
SCHEMBL23176761 0.79 KMT2A (0.32) NPC1RAB9AKMT2A
SCHEMBL6912868 0.79 FAAH (0.41) KMT2A
SCHEMBL77034 0.79 FAAH (0.41) KMT2A
SCHEMBL8070156 0.79 FAAH (0.41) KMT2A
SCHEMBL6910342 0.78 KMT2A (0.37) NPC1RAB9AKMT2A
SCHEMBL15788938 0.78 KMT2A (0.37) NPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5773388-A Pyrimidine derivatives, herbicides and plant growth regulators NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1998-06-30 US disclosed
US-5716904-A FOR BROARD LEAF WEEDS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1998-02-10 US disclosed
EP-0764641-A1 NOVEL 4,5-DISUBSTITUTED PYRIMIDINE DERIVATIVE AND HERBICIDE NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1997-03-26 EP disclosed
EP-0713872-A1 NOVEL PYRIMIDINE DERIVATIVE, HERBICIDE AND PLANT GROWTH REGULATOR NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1996-05-29 EP disclosed