Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 9/20 | 0.49 |
| ▸ | AVPR1A | P37288 | 9/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560154 | 0.90 | MEN1 (0.51) | AVPR2AVPR1AMEN1ALDH1A1MAPT | |
| SCHEMBL8565959 | 0.87 | AVPR2 (0.50) | AVPR2AVPR1AALDH1A1MGLL | |
| SCHEMBL8562554 | 0.79 | AVPR2 (0.73) | AVPR2AVPR1A | |
| SCHEMBL8556841 | 0.79 | AVPR2 (0.65) | AVPR2AVPR1A | |
| SCHEMBL8561962 | 0.79 | AVPR2 (0.58) | AVPR2AVPR1A | |
| SCHEMBL8559571 | 0.78 | AVPR2 (0.62) | AVPR2AVPR1A | |
| SCHEMBL8558803 | 0.78 | NAMPT (0.57) | AVPR2AVPR1A | |
| SCHEMBL8563337 | 0.77 | AVPR2 (0.51) | AVPR2AVPR1AHSD17B3 | |
| SCHEMBL8944480 | 0.76 | AVPR2 (0.59) | AVPR2AVPR1A | |
| SCHEMBL8561780 | 0.76 | AVPR2 (0.54) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |