Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3969316 | 0.85 | KDM4E (0.50) | ALDH1A1KDM4EUSP2ALOX15POLB | |
| SCHEMBL9621208 | 0.85 | KDM4E (0.50) | ALDH1A1KDM4EUSP2ALOX15POLB | |
| SCHEMBL8745307 | 0.83 | SMN1; SMN2 (0.58) | ALDH1A1KDM4EUSP2ALOX15POLB | |
| SCHEMBL9643851 | 0.83 | MEN1 (0.50) | USP2MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL13541637 | 0.83 | ALDH1A1 (0.53) | ALDH1A1KDM4EUSP2ALOX15POLB | |
| SCHEMBL8559136 | 0.82 | KDM4E (0.57) | ALDH1A1KDM4EUSP2ALOX15MAPT | |
| SCHEMBL8482310 | 0.82 | ALDH1A1 (0.45) | ALDH1A1KDM4EUSP2ALOX15POLB | |
| SCHEMBL9615184 | 0.82 | ALDH1A1 (0.52) | ALDH1A1KDM4EUSP2ALOX15POLB | |
| SCHEMBL15834423 | 0.81 | ALDH1A1 (0.48) | ALDH1A1KDM4EUSP2ALOX15POLB | |
| SCHEMBL5557273 | 0.81 | ALDH1A1 (0.48) | ALDH1A1KDM4EUSP2ALOX15POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4120065-A | — | — | None | — | — | JP | disclosed |
| EP-0700392-B1 | USE OF MACROCYCLIC METAL COMPLEXES AS TEMPERATURE PROBES | SCHERING AG (DE) | 1998-12-09 | — | — | EP | disclosed |
| US-5747000-A | 1,4-7-TRIS-(CARBOXYMETHYL)-1,4,7,10-TETRAAZACYCLODODECANE DERIVATIVES; DETERMINING CHEMICAL SHIFT OF SIGNALS IN NUCLEAR MAGNETIC RESONANCE | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-05-05 | — | — | US | disclosed |
| EP-0596586-B1 | Process for the production of metal complexes of N-beta-hydroxalkyl-tri-N-carboxyalkyl-1,4,7,10-tetraazacyclododecane and derivatives thereof | SCHERING AG (DE) | 1997-01-22 | — | — | EP | disclosed |
| EP-0700392-A1 | USE OF MACROCYCLIC METAL COMPLEXES AS TEMPERATURE PROBES | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-03-13 | — | — | EP | disclosed |
| US-5410043-A | Chemical intermediate for metal complexes | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-04-25 | — | — | US | disclosed |
| WO-1994027977-A1 | USE OF MACROCYCLIC METAL COMPLEXES AS TEMPERATURE PROBES | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-12-08 | — | — | WO | disclosed |
| EP-0596586-A1 | Process for the production of metal complexes of N-beta-hydroxalkyl-tri-N-carboxyalkyl-1,4,7,10-tetraazacyclododecane and derivatives thereof | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-05-11 | — | — | EP | disclosed |
| JP-H04120065-A | 10-(2'-HYDROXY-3'-ALKOXY)-1,4,7-TRISCARBOXYMETHYL-1,4,7,10-TETRAAZACYCLODODECANE | E R SQUIBB & SONS INC | 1992-04-21 | — | — | JP | disclosed |
| EP-0434345-A1 | 10-(2'-hydroxy-3'-alkoxy)-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecanes | E.R. SQUIBB & SONS, INC. (US) | 1991-06-26 | — | — | EP | disclosed |