Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3966966 | 0.86 | SMN1; SMN2 (0.73) | SMN1; SMN2MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL4446649 | 0.86 | SMN1; SMN2 (0.73) | SMN1; SMN2MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL3970208 | 0.86 | SMN1; SMN2 (0.73) | SMN1; SMN2MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL8559427 | 0.83 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1L3MBTL1USP2 | |
| SCHEMBL9643851 | 0.80 | MEN1 (0.50) | MEN1KMT2AL3MBTL1USP2MAPT | |
| SCHEMBL25493043 | 0.80 | SMN1; SMN2 (0.65) | SMN1; SMN2MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL12228111 | 0.80 | SMN1; SMN2 (0.65) | SMN1; SMN2MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL15296507 | 0.80 | SMN1; SMN2 (0.65) | SMN1; SMN2MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL25493039 | 0.80 | SMN1; SMN2 (0.65) | SMN1; SMN2MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL8559136 | 0.79 | KDM4E (0.57) | MEN1KMT2AALDH1A1L3MBTL1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596586-B1 | Process for the production of metal complexes of N-beta-hydroxalkyl-tri-N-carboxyalkyl-1,4,7,10-tetraazacyclododecane and derivatives thereof | SCHERING AG (DE) | 1997-01-22 | — | — | EP | disclosed |
| US-5410043-A | Chemical intermediate for metal complexes | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-04-25 | — | — | US | disclosed |
| EP-0596586-A1 | Process for the production of metal complexes of N-beta-hydroxalkyl-tri-N-carboxyalkyl-1,4,7,10-tetraazacyclododecane and derivatives thereof | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-05-11 | — | — | EP | disclosed |