Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.41 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12900477 | 0.83 | MEN1 (0.45) | CA1CA2MEN1KMT2AMAPT | |
| SCHEMBL7014244 | 0.83 | MEN1 (0.48) | CA1CA2MEN1KMT2AMAPT | |
| SCHEMBL7016019 | 0.75 | L3MBTL1 (0.50) | CA1CA2MEN1KMT2AMAPT | |
| SCHEMBL18976162 | 0.75 | MEN1 (0.67) | CA1CA2MEN1KMT2AMAPT | |
| SCHEMBL12900467 | 0.71 | DCK (0.43) | ALDH1A1LMNAPOLB | |
| SCHEMBL8559503 | 0.71 | CA1 (1.00) | CA1CA2KMT2AMAPTALDH1A1 | |
| SCHEMBL12932953 | 0.71 | HTR6 (0.43) | LMNAMMP2TSHR | |
| SCHEMBL19876738 | 0.70 | CA1 (0.50) | CA1CA2MEN1KMT2AMAPT | |
| SCHEMBL29605398 | 0.70 | CA1 (0.50) | CA1CA2MEN1KMT2AMAPT | |
| SCHEMBL26969417 | 0.70 | CA1 (0.50) | CA1CA2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877022-B1 | Sulfonylpyrimidine derivatives with anticancer activity | RUDJER BOSKOVIC INST (HR) | 2003-04-16 | — | — | EP | claimed |
| EP-0877022-A1 | Synthesis of the sulfonylpyrimidine derivatives with anticancer activity | Herbos d.d. (HR) | 1998-11-11 | — | — | EP | claimed |
| EP-0877022-A1 | Synthesis of the sulfonylpyrimidine derivatives with anticancer activity | Herbos d.d. (HR) | 1998-11-11 | — | — | EP | disclosed |