Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2B | Q13554 | 3/20 | 0.34 |
| ▸ | CAMK2G | Q13555 | 3/20 | 0.34 |
| ▸ | CAMK2D | Q13557 | 3/20 | 0.34 |
| ▸ | CAMK2A | Q9UQM7 | 3/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.34 |
| ▸ | CDK4 | P11802 | 2/20 | 0.34 |
| ▸ | CCND1 | P24385 | 2/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.33 |
| ▸ | WEE1 | P30291 | 3/20 | 0.33 |
| ▸ | PRKCG | P05129 | 2/20 | 0.32 |
| ▸ | PRKCB | P05771 | 2/20 | 0.32 |
| ▸ | PRKCA | P17252 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555433 | 0.87 | PRKCG (0.39) | CAMK2BCAMK2GCAMK2DCAMK2ACDK2 | |
| SCHEMBL8559639 | 0.77 | — | — | |
| SCHEMBL1234203 | 0.75 | GSK3B (0.39) | KDM4EALDH1A1CYP1A2HPGDCASP1 | |
| SCHEMBL4026807 | 0.74 | GSK3B (0.38) | KDM4EALDH1A1CYP1A2HPGDCASP1 | |
| SCHEMBL133934 | 0.74 | GSK3B (0.38) | KDM4EALDH1A1CYP1A2HPGDCASP1 | |
| SCHEMBL9152783 | 0.74 | GSK3B (0.38) | KDM4EALDH1A1CYP1A2HPGDCASP1 | |
| SCHEMBL4909203 | 0.74 | GSK3B (0.38) | KDM4EALDH1A1CYP1A2HPGDCASP1 | |
| SCHEMBL8938070 | 0.74 | GSK3B (0.38) | KDM4EALDH1A1CYP1A2HPGDCASP1 | |
| SCHEMBL9151570 | 0.74 | GSK3B (0.38) | KDM4EALDH1A1CYP1A2HPGDCASP1 | |
| SCHEMBL31036258 | 0.74 | GSK3B (0.38) | KDM4EALDH1A1CYP1A2HPGDCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575954-B1 | Aminoalkylcarbamic esters of eseroline suitable for use as cholinesterase acitivity inhibitors and relative preparation process | MEDIOLANUM FARMACEUTICI SRL (IT) | 1998-09-02 | — | — | EP | disclosed |