Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCG | P05129 | 7/20 | 0.39 |
| ▸ | PRKCB | P05771 | 6/20 | 0.39 |
| ▸ | PRKCA | P17252 | 6/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 8/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.37 |
| ▸ | CDK1 | P06493 | 2/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | PRKACG | P22612 | 1/20 | 0.37 |
| ▸ | PRKACB | P22694 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.37 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.37 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559526 | 0.87 | CAMK2B (0.34) | PRKCGPRKCBPRKCADPP4GSK3B | |
| SCHEMBL8664540 | 0.74 | DRD2 (0.52) | SLC6A4 | |
| SCHEMBL1256987 | 0.72 | KDM4E (0.40) | GSK3BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL34459998 | 0.72 | MAPT (0.43) | PRKCGPRKCBPRKCAGSK3BOPRD1 | |
| SCHEMBL34460000 | 0.70 | ALDH1A1 (0.38) | KDM4EALDH1A1HSD17B10MEN1MAPT | |
| SCHEMBL12875827 | 0.70 | MC4R (0.50) | DPP4KDM4EALDH1A1NPSR1SLC6A2 | |
| SCHEMBL9136212 | 0.70 | ALDH1A1 (0.38) | GSK3BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8559801 | 0.70 | SLC6A2 (0.35) | GSK3BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL30876940 | 0.69 | KDM4E (0.43) | GSK3BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8074204 | 0.69 | POLB (0.37) | GSK3BKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575954-B1 | Aminoalkylcarbamic esters of eseroline suitable for use as cholinesterase acitivity inhibitors and relative preparation process | MEDIOLANUM FARMACEUTICI SRL (IT) | 1998-09-02 | — | — | EP | disclosed |
| US-5424451-A | Used as cholinesterase activity inhibitors | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1995-06-13 | — | — | US | disclosed |
| US-5302593-A | Aminoalkylcarbamic esters of eseroline suitable for use as chlorinesterase activity inhibitors | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1994-04-12 | — | — | US | disclosed |
| EP-0575954-A1 | Aminoalkylcarbamic esters of eseroline suitable for use as cholinesterase acitivity inhibitors and relative preparation process | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1993-12-29 | — | — | EP | disclosed |