Phosphine

Phosphine

SCHEMBL8559532

CCc1c(Br)ccc(CCO)c1CC.P

nearest known ligand 0.30

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.30
GABRB2 P47870 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphine SCHEMBL9717357 0.81 GABRA1 (0.41) GABRA1GABRB2
SCHEMBL8090788 0.79 GABRA1 (0.42) GABRA1GABRB2
SCHEMBL12387626 0.78 GABRA1 (0.33) GABRA1GABRB2
SCHEMBL12387633 0.78 GABRA1 (0.33) GABRA1GABRB2
SCHEMBL952931 0.76 GABRA1 (0.37) GABRA1GABRB2
SCHEMBL14994059 0.76 NOS3 (0.34)
SCHEMBL14370241 0.74 PRKCI (0.33) GABRA1GABRB2
SCHEMBL23856281 0.69 GABRA1 (0.41) GABRA1GABRB2
SCHEMBL954703 0.68 GABRA1 (0.37) GABRA1GABRB2
SCHEMBL13002847 0.68 THRB (0.38) GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5958906-A Phospholipid derivatives containing higher elements of the fifth main group ASTA-MEDICA AKTIENGESELLSCHAFT (DE) 1999-09-28 US disclosed
US-5637577-A TREATMENT OF POTOZOAL DISEASES ASTA MEDICA AKTIENGESELLSCHAFT (DE) 1997-06-10 US disclosed
US-5449798-A Phospholipid derivatives containing higher elements of the fifth group ASTA MEDICA AKTIENGESELLSCHAFT (DE) 1995-09-12 US disclosed