Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561526 | 0.85 | HPGD (0.39) | HPGDL3MBTL1THRBATMCASP6 | |
| SCHEMBL789907 | 0.85 | EPHX1 (0.55) | HPGDL3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL788997 | 0.82 | EPHX2 (0.36) | HPGDTSHR | |
| SCHEMBL23042307 | 0.80 | L3MBTL1 (0.59) | HPGDL3MBTL1THRBATMCASP6 | |
| SCHEMBL15114600 | 0.80 | FPR2 (0.41) | ALDH1A1 | |
| SCHEMBL8223985 | 0.80 | HPGD (0.62) | HPGDL3MBTL1THRBATMCASP6 | |
| SCHEMBL8806885 | 0.78 | KMT2A (0.43) | L3MBTL1GAASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL2597299 | 0.78 | EPHX1 (0.53) | HPGDL3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL5900372 | 0.77 | KMT2A (0.63) | HPGDL3MBTL1THRBATMGAA | |
| SCHEMBL789128 | 0.77 | EPHX2 (0.35) | KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804577-A | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1998-09-08 | — | — | US | disclosed |
| CN-1150950-A | Cephalosporin derivatives | HOFFMANN LA ROCHE (CH) | 1997-06-04 | — | — | CN | disclosed |
| EP-0761673-A1 | Cephalosporin derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1997-03-12 | — | — | EP | disclosed |