Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LTC4S | Q16873 | 4/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NEK2 | P51955 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8565268 | 0.91 | DPP4 (0.42) | KDM4ESMN1; SMN2ALDH1A1HPGDDHFR | |
| SCHEMBL9542072 | 0.80 | PDE4B (0.43) | SMN1; SMN2ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL8564146 | 0.79 | CSF1R (0.50) | SMN1; SMN2MEN1KMT2ANPC1MAPT | |
| SCHEMBL8324245 | 0.76 | TSHR (0.42) | KDM4ESMN1; SMN2ALDH1A1HSD17B10HPGD | |
| SCHEMBL8326372 | 0.74 | TSHR (0.40) | KDM4ESMN1; SMN2ALDH1A1HSD17B10HPGD | |
| SCHEMBL8563378 | 0.72 | PDE4B (0.59) | SMN1; SMN2ALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL8565303 | 0.72 | CSF1R (0.62) | — | |
| SCHEMBL8559490 | 0.72 | CSF1R (0.48) | — | |
| Hydrochloric Acid SCHEMBL811230 | 0.72 | PDE4B (0.58) | SMN1; SMN2ALDH1A1MEN1KMT2ATP53 | |
| Hydrochloric Acid SCHEMBL8565607 | 0.71 | CSF1R (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618916-B1 | ANTI-RHEUMATIC NAPHTHYRIDINE DERIVATIVES | KNOLL AG (DE) | 1998-09-23 | — | — | EP | disclosed |