Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855164 | 0.81 | MAOA (0.38) | MAOAMAOBALOX5KCNJ1LMNA | |
| SCHEMBL855077 | 0.76 | ALOX5 (0.39) | MAOAMAOBALOX5KCNJ1LMNA | |
| SCHEMBL698199 | 0.73 | PIM1 (0.48) | MAOAMAOBALOX5KCNJ1CA1 | |
| SCHEMBL286612 | 0.69 | KCNJ1 (0.44) | MAOAMAOBALOX5KCNJ1LMNA | |
| SCHEMBL286354 | 0.68 | KCNJ1 (0.46) | MAOAMAOBALOX5KCNJ1LMNA | |
| SCHEMBL29440632 | 0.68 | MAOA (0.62) | MAOAMAOBLMNAGAAMAPT | |
| SCHEMBL854664 | 0.68 | MAOA (0.62) | MAOAMAOBLMNAGAAMAPT | |
| SCHEMBL855079 | 0.68 | KCNJ1 (0.46) | MAOAMAOBALOX5KCNJ1LMNA | |
| SCHEMBL855514 | 0.67 | CYP3A4 (0.53) | MAOAMAOBKCNJ1LMNAGAA | |
| SCHEMBL23496685 | 0.66 | KCNJ1 (0.44) | MAOAMAOBALOX5KCNJ1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105849094-B | The manufacture method of halogen-substituted phthalein | 住友化学株式会社 | 2018-04-10 | — | — | CN | disclosed |
| CN-105849094-A | Method for producing halogen-substituted phthalide | 住友化学株式会社 | 2016-08-10 | — | — | CN | disclosed |
| US-8604221-B2 | Production method of halogen-substituted phthalide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-12-10 | — | — | US | disclosed |
| US-20120142946-A1 | PRODUCTION METHOD OF HALOGEN-SUBSTITUTED PHTHALIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-06-07 | — | — | US | disclosed |
| EP-2433933-A1 | PRODUCTION METHOD OF HALOGEN-SUBSTITUTED PHTHALIDE | Sumitomo Chemical Company, Limited (JP) | 2012-03-28 | — | — | EP | disclosed |