Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 4/20 | 0.51 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558397 | 0.85 | SMN1; SMN2 (0.47) | AVPR2AVPR1ASMN1; SMN2RAB9AKMT2A | |
| SCHEMBL7319409 | 0.81 | AVPR2 (0.66) | AVPR2AVPR1ASMN1; SMN2RAB9AKMT2A | |
| SCHEMBL8819120 | 0.80 | AVPR2 (0.75) | AVPR2AVPR1A | |
| SCHEMBL8820731 | 0.80 | AVPR1A (0.63) | AVPR2AVPR1A | |
| SCHEMBL8559469 | 0.80 | AVPR2 (0.65) | AVPR2AVPR1ASMN1; SMN2RAB9AKMT2A | |
| SCHEMBL8820647 | 0.78 | AVPR2 (0.50) | AVPR2AVPR1ASMN1; SMN2RAB9A | |
| SCHEMBL8820706 | 0.78 | AVPR1A (0.60) | AVPR2AVPR1AALDH1A1 | |
| SCHEMBL8820413 | 0.78 | AVPR2 (0.56) | AVPR2AVPR1AKMT2AMEN1 | |
| SCHEMBL8818380 | 0.78 | AVPR2 (0.60) | AVPR2AVPR1AALDH1A1 | |
| SCHEMBL8820751 | 0.78 | AVPR1A (0.67) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |