Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | FYN | P06241 | 2/20 | 0.67 |
| ▸ | ACHE | P22303 | 2/20 | 0.67 |
| ▸ | AHR | P35869 | 2/20 | 0.67 |
| ▸ | LCK | P06239 | 1/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HPRT1 | P00492 | 4/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3-Methylcholanthrene SCHEMBL29444145 | 0.80 | ALDH1A1 (1.00) | ALDH1A1CYP1A2MAPTFYNACHE | |
| 3-Methylcholanthrene SCHEMBL29397062 | 0.80 | ALDH1A1 (1.00) | ALDH1A1CYP1A2MAPTFYNACHE | |
| 3-Methylcholanthrene SCHEMBL156129 | 0.80 | ALDH1A1 (1.00) | ALDH1A1CYP1A2MAPTFYNACHE | |
| 3-Methylcholanthrene SCHEMBL2958054 | 0.79 | ALDH1A1 (0.97) | ALDH1A1CYP1A2MAPTFYNACHE | |
| 3-Methylcholanthrene SCHEMBL27621124 | 0.79 | ALDH1A1 (0.97) | ALDH1A1CYP1A2MAPTFYNACHE | |
| Cholanthrene SCHEMBL9048 | 0.75 | ALDH1A1 (0.65) | ALDH1A1CYP1A2MAPTFYNACHE | |
| SCHEMBL10484179 | 0.72 | HPRT1 (0.56) | ALDH1A1CYP1A2MAPTHPGDHSD17B10 | |
| SCHEMBL28783299 | 0.71 | CYP1A2 (0.62) | ALDH1A1CYP1A2MAPTFYNACHE | |
| SCHEMBL7794322 | 0.69 | CYP1A2 (0.48) | ALDH1A1CYP1A2MAPTFYNACHE | |
| SCHEMBL5379988 | 0.68 | CYP11B1 (0.44) | ALDH1A1CYP1A2MAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240272149-A1 | DETECTION OF BIOACTIVE AGENTS IN A SURROUNDING MEDIUM | PHILIP MORRIS PRODUCTS S.A. (CH) | 2024-08-15 | — | — | US | disclosed |
| EP-4413367-A1 | DETECTION OF BIOACTIVE AGENTS IN A SURROUNDING MEDIUM | Philip Morris Products S.A. (CH) | 2024-08-14 | — | — | EP | disclosed |
| WO-2023057602-A1 | DETECTION OF BIOACTIVE AGENTS IN A SURROUNDING MEDIUM | PHILIP MORRIS PRODUCTS S.A. (CH) | 2023-04-13 | — | — | WO | disclosed |
| US-10064834-B2 | Carbidopa for the treatment of cancer | TEXAS TECH UNIVERSITY SYSTEM (US) | 2018-09-04 | — | — | US | disclosed |
| US-20170319527-A1 | Carbidopa for the Treatment of Cancer | TEXAS TECH UNIVERSITY SYSTEM | 2017-11-09 | — | — | US | disclosed |
| US-5766588-A | Tumor immunotherapy using anti-idiotypic antibodies | ONCOGEN (US) | 1998-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170319527-A1 | Carbidopa for the Treatment of Cancer | IDO1, IDO2, INMT | ALDH1A1 934/4885CYP1A2 2508/4885MAPT 4199/4885 |
| US-10064834-B2 | Carbidopa for the treatment of cancer | IDO1, IDO2, INMT | ALDH1A1 934/4885CYP1A2 2508/4885MAPT 4199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.