Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7661252 | 0.84 | ADORA1 (0.47) | ADORA1ADORA3MEN1KMT2AADORA2A | |
| SCHEMBL7656833 | 0.83 | KMT2A (0.50) | ADORA1ADORA3MEN1KMT2AADORA2A | |
| SCHEMBL7657404 | 0.83 | TSHR (0.46) | ADORA1ADORA3MEN1KMT2AADORA2A | |
| SCHEMBL8560750 | 0.77 | PDE4A (0.52) | ADORA1ADORA3ADORA2AADORA2BHSD17B10 | |
| SCHEMBL7001583 | 0.75 | ADORA2A (0.49) | ADORA3MEN1KMT2AADORA2AADORA2B | |
| SCHEMBL9122257 | 0.74 | ADORA1 (1.00) | ADORA1ADORA3MEN1KMT2AADORA2A | |
| SCHEMBL6868442 | 0.73 | ADORA1 (1.00) | ADORA1ADORA3MEN1KMT2AADORA2A | |
| SCHEMBL8559651 | 0.73 | ADORA2B (0.61) | ADORA1ADORA3MEN1KMT2AADORA2A | |
| SCHEMBL8562832 | 0.72 | ADORA2B (0.43) | ADORA1ADORA3ADORA2AADORA2BKDM4E | |
| SCHEMBL8561695 | 0.70 | ADORA2B (0.54) | ADORA1ADORA3MEN1KMT2AADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0880524-A1 | NEW TRIAZOLOPURINES, METHOD OF PREPARING THEM AND THEIR USE AS DRUGS | Boehringer Ingelheim Pharma KG (DE) | 1998-12-02 | — | — | EP | disclosed |
| WO-1998003511-A1 | NEW TRIAZOLOPURINES, METHOD OF PREPARING THEM AND THEIR USE AS DRUGS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1998-01-29 | — | — | WO | disclosed |