Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.55 |
| ▸ | PTPN5 | P54829 | 8/20 | 0.55 |
| ▸ | PTPN2 | P17706 | 7/20 | 0.55 |
| ▸ | HSPD1 | P10809 | 4/20 | 0.54 |
| ▸ | HSPE1 | P61604 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | USP1 | O94782 | 1/20 | 0.47 |
| ▸ | USP19 | O94966 | 1/20 | 0.47 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560329 | 0.86 | PTGS2 (0.52) | MAPTMEN1KMT2APTPN1PTPN5 | |
| SCHEMBL8559926 | 0.81 | MAPT (0.47) | MAPTMEN1KMT2APTPN1PTPN5 | |
| SCHEMBL8556139 | 0.81 | MAPT (0.47) | MAPTMEN1KMT2APTPN1PTPN5 | |
| SCHEMBL8558820 | 0.81 | MAPT (0.47) | MAPTMEN1KMT2APTPN1PTPN5 | |
| SCHEMBL8557761 | 0.81 | MAPT (0.49) | MAPTMEN1KMT2APTPN1PTPN5 | |
| SCHEMBL8558072 | 0.80 | PTGS2 (0.46) | MAPTMEN1KMT2APTPN1PTPN5 | |
| SCHEMBL8558727 | 0.80 | MAPT (0.45) | MAPTMEN1KMT2APTPN1PTPN5 | |
| SCHEMBL8558401 | 0.80 | MAPT (0.45) | MAPTMEN1KMT2APTPN1PTPN5 | |
| SCHEMBL5694177 | 0.80 | EDNRB (0.51) | MAPTMEN1KMT2APTPN1PTPN5 | |
| SCHEMBL8555624 | 0.80 | MAPT (0.58) | MAPTMEN1KMT2APTPN1PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |