Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.55 |
| ▸ | PTPN5 | P54829 | 8/20 | 0.55 |
| ▸ | PTPN2 | P17706 | 7/20 | 0.55 |
| ▸ | HSPD1 | P10809 | 4/20 | 0.54 |
| ▸ | HSPE1 | P61604 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | USP1 | O94782 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555077 | 0.85 | PTGS2 (0.51) | MAPTPTPN1PTPN5PTPN2HSPD1 | |
| SCHEMBL8559708 | 0.81 | MAPT (0.46) | MAPTPTPN1PTPN5PTPN2HSPD1 | |
| SCHEMBL8560089 | 0.80 | MAPT (0.58) | MAPTPTPN1PTPN5PTPN2HSPD1 | |
| SCHEMBL8555123 | 0.78 | AR (0.51) | MAPTPTPN1PTPN5PTPN2MEN1 | |
| SCHEMBL8560251 | 0.76 | HDAC6 (0.48) | MAPTPTPN1PTPN5PTPN2MEN1 | |
| SCHEMBL8556824 | 0.76 | HSD11B1 (0.44) | MAPTPTPN1PTPN5PTPN2HSPD1 | |
| SCHEMBL8555985 | 0.75 | NR4A2 (0.54) | MAPTPTPN1PTPN5PTPN2MEN1 | |
| SCHEMBL8560630 | 0.74 | MAPT (0.49) | MAPTPTPN1PTPN5PTPN2MEN1 | |
| SCHEMBL8557930 | 0.74 | HSD11B1 (0.44) | MAPTPTPN1PTPN5PTPN2MEN1 | |
| SCHEMBL8558438 | 0.73 | HPGD (0.41) | MAPTPTPN1PTPN5PTPN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |