Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8021031 | 0.91 | L3MBTL1 (0.63) | L3MBTL1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL2457012 | 0.89 | KMT2A (0.64) | L3MBTL1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL29651126 | 0.85 | KMT2A (0.76) | L3MBTL1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL1746797 | 0.85 | KMT2A (0.76) | L3MBTL1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL22864630 | 0.83 | L3MBTL1 (0.47) | L3MBTL1KMT2AMEN1CRHBPCRHR2 | |
| SCHEMBL3159607 | 0.82 | L3MBTL1 (0.56) | L3MBTL1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL6179129 | 0.82 | L3MBTL1 (0.56) | L3MBTL1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL30958459 | 0.82 | L3MBTL1 (0.56) | L3MBTL1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL30207773 | 0.81 | L3MBTL1 (0.55) | L3MBTL1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL28247852 | 0.81 | L3MBTL1 (0.55) | L3MBTL1KMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719141-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |
| CN-1169986-A | 2.9-diamino-and 2-amino-8-carbamoyl-4-hydroxy-aldanoic acid amide derivatives | CIBA GEIGY AG (CH) | 1998-01-14 | — | — | CN | disclosed |