Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.41 |
| ▸ | GBA1 | P04062 | 4/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.36 |
| ▸ | GBA2 | Q9HCG7 | 9/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27958323 | 0.87 | GBA1 (0.37) | S1PR1S1PR3S1PR5GBA1 | |
| SCHEMBL8557666 | 0.83 | S1PR1 (0.41) | S1PR1S1PR3S1PR5GBA1S1PR4 | |
| SCHEMBL27793814 | 0.79 | MAPK1 (0.33) | — | |
| SCHEMBL28764468 | 0.78 | ALDH1A1 (0.30) | — | |
| SCHEMBL27660277 | 0.78 | ALDH1A1 (0.30) | — | |
| SCHEMBL7392194 | 0.77 | MAOB (0.44) | — | |
| SCHEMBL10596931 | 0.76 | OPRD1 (0.36) | S1PR1S1PR3S1PR5GBA1S1PR4 | |
| Hydrochloric Acid SCHEMBL7403380 | 0.76 | MAOB (0.43) | — | |
| SCHEMBL12513822 | 0.76 | CXCR4 (0.51) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL25956532 | 0.76 | CXCR4 (0.51) | S1PR1S1PR3S1PR5S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853615-A1 | PIPERIDINE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | NEUROSEARCH A/S (DK) | 1998-07-22 | — | — | EP | disclosed |
| WO-1997010212-A1 | PIPERIDINE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | NEUROSEARCH A/S (DK) | 1997-03-20 | — | — | WO | disclosed |