Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL681184 | 0.91 | ELANE (0.34) | TSHRELANEALDH1A1POLBMAPT | |
| SCHEMBL8560414 | 0.87 | TSHR (0.31) | TSHR | |
| SCHEMBL19680509 | 0.84 | TSHR (0.57) | TSHRALDH1A1POLB | |
| SCHEMBL217246 | 0.83 | ALDH1A1 (0.41) | TSHRELANEALDH1A1POLBMAPT | |
| SCHEMBL7606317 | 0.81 | ALDH1A1 (0.43) | TSHRALDH1A1MAPT | |
| SCHEMBL217247 | 0.81 | TSHR (0.33) | TSHRELANEALDH1A1MAPTNPC1 | |
| SCHEMBL11631362 | 0.80 | ELANE (0.32) | TSHRELANEALDH1A1POLBMAPT | |
| SCHEMBL22799098 | 0.79 | GRIN2D (0.37) | — | |
| SCHEMBL7370005 | 0.79 | ALDH1A1 (0.32) | ALDH1A1POLBMAPTNPC1 | |
| SCHEMBL6066229 | 0.79 | ALOX15 (0.46) | TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559533-B1 | Process for preparing beta-lactam derivative and synthetic intermediate thereof | TANABE SEIYAKU CO (JP) | 1998-07-22 | — | — | EP | disclosed |
| US-5589592-A | Process for preparing β-lactam derivative and synthetic intermediate | TANABE SEIYAKU CO., LTD. (JP) | 1996-12-31 | — | — | US | disclosed |
| US-5414081-A | Treating a 1-aza-3-thiabicycloalkane with base and phosphine or phosphite desulfurizing agent, and reacting the product with an active esterifying agent | TANABE SEIYAKU CO., LTD. (JP) | 1995-05-09 | — | — | US | disclosed |
| EP-0559533-A1 | Process for preparing beta-lactam derivative and synthetic intermediate thereof | TANABE SEIYAKU CO., LTD. (JP) | 1993-09-08 | — | — | EP | disclosed |