Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8520711 | 1.00 | PRCP (0.40) | PRCPGAAMAPTHPGDMAPK1 | |
| SCHEMBL8413432 | 0.77 | PRCP (0.45) | PRCPCHRM1SIGMAR1 | |
| SCHEMBL8410312 | 0.77 | PRCP (0.45) | PRCPCHRM1SIGMAR1 | |
| SCHEMBL8410313 | 0.77 | PRCP (0.45) | PRCPCHRM1SIGMAR1 | |
| SCHEMBL8558759 | 0.76 | PRCP (0.49) | PRCPGAAMAPTHPGDMAPK1 | |
| SCHEMBL8205125 | 0.76 | PRCP (0.49) | PRCPGAAMAPTHPGDMAPK1 | |
| SCHEMBL8205657 | 0.74 | PRCP (0.37) | PRCPGAAMAPTHPGDMAPK1 | |
| SCHEMBL7703496 | 0.67 | SIGMAR1 (0.53) | PRCPSIGMAR1 | |
| SCHEMBL28764487 | 0.63 | SIGMAR1 (0.52) | PRCPSIGMAR1 | |
| SCHEMBL7701926 | 0.60 | SIGMAR1 (0.40) | PRCPCHRM1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972952-A | THERAPY FOR STROKE, NERVOUS SYSTEM DISORDERS, ALZHEIMER'SDISEASE | LE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1999-10-26 | — | — | US | disclosed |