Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8205125 | 1.00 | PRCP (0.49) | PRCPSIGMAR1MEN1KMT2ASLC6A2 | |
| SCHEMBL8205657 | 0.79 | PRCP (0.37) | PRCPSIGMAR1SLC6A2SLC6A9GAA | |
| Gacyclidine SCHEMBL397836 | 0.78 | SIGMAR1 (0.57) | PRCPSIGMAR1MEN1KMT2ASLC6A2 | |
| Gacyclidine SCHEMBL3457748 | 0.78 | SIGMAR1 (0.57) | PRCPSIGMAR1MEN1KMT2ASLC6A2 | |
| Gacyclidine SCHEMBL7190367 | 0.78 | SIGMAR1 (0.57) | PRCPSIGMAR1MEN1KMT2ASLC6A2 | |
| Gacyclidine SCHEMBL4465879 | 0.78 | SIGMAR1 (0.57) | PRCPSIGMAR1MEN1KMT2ASLC6A2 | |
| Gacyclidine SCHEMBL5398234 | 0.77 | SIGMAR1 (0.56) | PRCPSIGMAR1MEN1KMT2ASLC6A2 | |
| Gacyclidine SCHEMBL1662223 | 0.77 | SIGMAR1 (0.56) | PRCPSIGMAR1MEN1KMT2ASLC6A2 | |
| SCHEMBL8520711 | 0.76 | PRCP (0.40) | PRCPSIGMAR1GAAMAPTHPGD | |
| SCHEMBL8560436 | 0.76 | PRCP (0.40) | PRCPSIGMAR1GAAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972952-A | THERAPY FOR STROKE, NERVOUS SYSTEM DISORDERS, ALZHEIMER'SDISEASE | LE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1999-10-26 | — | — | US | claimed |
| US-5972952-A | THERAPY FOR STROKE, NERVOUS SYSTEM DISORDERS, ALZHEIMER'SDISEASE | LE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1999-10-26 | — | — | US | disclosed |
| US-5972952-A | THERAPY FOR STROKE, NERVOUS SYSTEM DISORDERS, ALZHEIMER'SDISEASE | LE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1999-10-26 | — | — | US | disclosed |