Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555187 | 0.92 | MAPT (0.46) | MAPTALDH1A1SLC40A1LMNAPDE4A | |
| SCHEMBL8559711 | 0.90 | MAPT (0.47) | MAPTALDH1A1SLC40A1LMNACCNT1 | |
| SCHEMBL8559359 | 0.90 | ALDH1A1 (0.47) | MAPTALDH1A1SLC40A1LMNAKIT | |
| SCHEMBL8560513 | 0.89 | MAPT (0.49) | MAPTALDH1A1SLC40A1LMNAPDE4A | |
| SCHEMBL8560974 | 0.87 | ALDH1A1 (0.44) | MAPTALDH1A1SLC40A1CCNT1CDK9 | |
| SCHEMBL8556318 | 0.87 | ALDH1A1 (0.44) | MAPTALDH1A1SLC40A1LMNAKIT | |
| SCHEMBL8557761 | 0.84 | MAPT (0.49) | MAPTALDH1A1SLC40A1LMNALIMK2 | |
| SCHEMBL8556526 | 0.84 | MAPT (0.46) | MAPTALDH1A1SLC40A1LMNAPDE4A | |
| SCHEMBL8555603 | 0.84 | MAPT (0.48) | MAPTALDH1A1SLC40A1LMNAPDE4A | |
| SCHEMBL8559666 | 0.83 | ALDH1A1 (0.50) | MAPTALDH1A1SLC40A1LMNAPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |