Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 6/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 3/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557951 | 0.90 | ALDH1A1 (0.49) | ALDH1A1MAPTCDK9CCNT1SCN9A | |
| SCHEMBL8557661 | 0.89 | ALDH1A1 (0.45) | ALDH1A1MAPTCDK9CCNT1SCN9A | |
| SCHEMBL8560880 | 0.89 | MAPT (0.48) | ALDH1A1MAPTCDK9CCNT1SCN9A | |
| SCHEMBL8559711 | 0.87 | MAPT (0.47) | ALDH1A1MAPTCDK9CCNT1SLC40A1 | |
| SCHEMBL8560599 | 0.87 | MAPT (0.46) | ALDH1A1MAPTCDK9CCNT1SLC40A1 | |
| SCHEMBL8555187 | 0.85 | MAPT (0.46) | ALDH1A1MAPTSLC40A1PGR | |
| SCHEMBL8555068 | 0.85 | ALDH1A1 (0.50) | ALDH1A1MAPTSCN9ASMN1; SMN2SLC40A1 | |
| SCHEMBL8554227 | 0.85 | CCNT1 (0.49) | ALDH1A1MAPTCDK9CCNT1SMN1; SMN2 | |
| SCHEMBL8556318 | 0.85 | ALDH1A1 (0.44) | ALDH1A1MAPTSMN1; SMN2SLC40A1PGR | |
| SCHEMBL8556679 | 0.84 | ALDH1A1 (0.46) | ALDH1A1MAPTCDK9CCNT1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |