Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MGMT | P16455 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558130 | 0.83 | NOS2 (0.44) | MAPTLMNAHTTKDM4EMITF | |
| SCHEMBL5145767 | 0.81 | MAPT (0.47) | MAPTLMNAHTTKDM4EMITF | |
| SCHEMBL27766587 | 0.81 | HTT (0.44) | MAPTLMNAHTTKDM4EMITF | |
| SCHEMBL9987621 | 0.80 | HTT (0.40) | MAPTLMNAHTTKDM4EMITF | |
| SCHEMBL8601080 | 0.79 | HTT (0.43) | MAPTLMNAHTTKDM4EMITF | |
| SCHEMBL8566254 | 0.79 | IKBKB (0.42) | MAPTLMNAHTTKDM4EMITF | |
| SCHEMBL8568292 | 0.79 | ALDH1A1 (0.39) | MAPTLMNAHTTKDM4ESMN1; SMN2 | |
| SCHEMBL4301431 | 0.78 | MAPT (0.38) | MAPTLMNAHTTKDM4EMITF | |
| SCHEMBL16919118 | 0.77 | HTT (0.51) | MAPTLMNAHTTKDM4EMITF | |
| SCHEMBL8560653 | 0.77 | MEN1 (0.37) | MAPTLMNAHTTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |