Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6994948 | 0.73 | L3MBTL1 (0.97) | L3MBTL1KDM4ECYP2C19POLBCYP2D6 | |
| Tert-Butylamine SCHEMBL28089931 | 0.72 | L3MBTL1 (0.83) | L3MBTL1KDM4ECYP2C19POLBCYP2D6 | |
| SCHEMBL28089929 | 0.71 | L3MBTL1 (0.57) | L3MBTL1KDM4ECYP2C19POLBCYP2D6 | |
| SCHEMBL21061629 | 0.69 | L3MBTL1 (0.82) | L3MBTL1KDM4ECYP2C19POLBCYP2D6 | |
| SCHEMBL21061969 | 0.69 | L3MBTL1 (0.82) | L3MBTL1KDM4ECYP2C19POLBCYP2D6 | |
| SCHEMBL8557410 | 0.68 | L3MBTL1 (0.51) | L3MBTL1KDM4ECYP2C19POLBALDH1A1 | |
| SCHEMBL3917901 | 0.68 | L3MBTL1 (0.60) | L3MBTL1KDM4ECYP2C19ALDH1A1MEN1 | |
| SCHEMBL7562443 | 0.67 | L3MBTL1 (0.58) | L3MBTL1KDM4ECYP2C19POLBALDH1A1 | |
| SCHEMBL7562439 | 0.67 | L3MBTL1 (0.58) | L3MBTL1KDM4ECYP2C19POLBALDH1A1 | |
| SCHEMBL13006881 | 0.67 | GAA (0.64) | KDM4ECYP2C19POLBCYP2D6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874809-A1 | CARBAMOYLOXY DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997025309-A1 | CARBAMOYLOXY DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 1997-07-17 | — | — | WO | disclosed |