Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.42 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14515118 | 0.77 | OPRM1 (0.41) | L3MBTL1KDM4ECYP2C19ALDH1A1HSD17B10 | |
| SCHEMBL9963444 | 0.76 | KCNA5 (0.50) | ALDH1A1TSHRCYP1A2KCNA5KCNE1 | |
| SCHEMBL1514881 | 0.75 | SLC6A4 (0.55) | ALDH1A1KCNA5KCNE1 | |
| SCHEMBL1991270 | 0.75 | POLB (0.51) | L3MBTL1ALDH1A1LMNAALOX12HSD17B10 | |
| SCHEMBL9933670 | 0.75 | SLC6A4 (0.55) | ALDH1A1KCNA5KCNE1 | |
| SCHEMBL8558345 | 0.73 | KDM4E (0.40) | KDM4ECYP2C19ALDH1A1TSHRHSD17B10 | |
| SCHEMBL1514908 | 0.73 | GPR119 (0.50) | POLB | |
| SCHEMBL9934875 | 0.73 | GPR119 (0.50) | POLB | |
| SCHEMBL38663417 | 0.73 | GPR119 (0.50) | POLB | |
| SCHEMBL4453658 | 0.72 | KDM4E (0.39) | L3MBTL1KDM4ECYP2C19ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874809-A1 | CARBAMOYLOXY DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997025309-A1 | CARBAMOYLOXY DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 1997-07-17 | — | — | WO | disclosed |